Patent · US Expired

Process for preparing optically active 2-halo-1-phenyl ethanol

US4857468A · kind A · utility

12Cited by
2References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 10, 1986
Grant dateAug 15, 1989
Priority date
Expiry dateApr 10, 2006

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/94
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A process for preparing optically active 2-halo-1-phenyl ethanol having the general formula [I*]: ##STR1## wherein X is a halogen atom, by asymmetrically reducing 2-halo-acetophenone having the general formula [II]: ##STR2## wherein X is as above, to give optically active 2-halo-1-phenyl ethanol, (R)-form or (S)-form, employing the microorganism. ##STR3## According to the present invention, optically active 2-halo-1-phenyl ethanol can be prepared with a good optical purity and yield in a simple process.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.