Process for preparing optically active 2-halo-1-phenyl ethanol
US4857468A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 10, 1986 |
| Grant date | Aug 15, 1989 |
| Priority date | — |
| Expiry date | Apr 10, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/94
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for preparing optically active 2-halo-1-phenyl ethanol having the general formula [I*]: ##STR1## wherein X is a halogen atom, by asymmetrically reducing 2-halo-acetophenone having the general formula [II]: ##STR2## wherein X is as above, to give optically active 2-halo-1-phenyl ethanol, (R)-form or (S)-form, employing the microorganism. ##STR3## According to the present invention, optically active 2-halo-1-phenyl ethanol can be prepared with a good optical purity and yield in a simple process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.