Virus inactivation
US4857514A · kind A · utility
4Cited by
1References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 17, 1985 |
| Grant date | Aug 15, 1989 |
| Priority date | — |
| Expiry date | Sep 17, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/685
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A virus having a lipid-containing capsid, such as AIDS virus, is inactivated by contacting the virus with an inactivating amount of phosphatidyl choline. Such a virus can be inactivated in fluids such as virus-contaminated body fluids or derivatives, e.g., blood or blood derivatives. The phosphatidyl choline can be present in an Active Lipid (AL) composition further comprising neutral lipids and phosphatidyl ethanolamine. Phosphatidyl choline, and an AL composition containing same, is useful for the treatment or prophylaxis of Acquired Immune Deficiency Syndrome (AIDS) in mammals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.