Quinuclidyl benzoxepins as 5-HT.sub.3 antagonists
US4857517A · kind A · utility
7Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 4, 1988 |
| Grant date | Aug 15, 1989 |
| Priority date | — |
| Expiry date | Feb 4, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D453/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Certain specific substituted 9-N-(1-azabicyclo-[2.2.2.]octan-3-yl)carboxamido-2,3,4,5-tetrahydro-1-benz oxepins and their valuable use as 5-HT.sub.3 antagonists having CNS and gastric prokinetic acticity and void of any significant D.sub.2 receptor binding properties are disclosed. Methods for their preparation also are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.