Process for the preparation of taxol and 10-deacetyltaxol
US4857653A · kind A · utility
196Cited by
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4Claims
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Key dates
| Filing date | Jul 14, 1987 |
| Grant date | Aug 15, 1989 |
| Priority date | — |
| Expiry date | Jul 14, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D305/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Taxol and 10-deacetyltaxol are prepared from a compound of formula: ##STR1## in which R' represents acetyl or 2,2,2-trichloroethoxycarbonyl radical, by removal of the t-butoxycarbonyl radical, benzoylation of the amine product obtained, and removal of the 2,2,2-trichloroethoxycarbonyl group(s).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.