Process for industrially separating biopolymers
US4859342A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jun 14, 1988 |
| Grant date | Aug 22, 1989 |
| Priority date | — |
| Expiry date | Jun 14, 2008 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/361
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A process and an apparatus for separating industrially a large amount of a biopolymer-containing sample by ion-exchange type column chromatography using the gradient elution method, wherein at least two precursor liquids for a mobile phase from liquid baths 3a and 3b are introduced into a mixing device 14 while the flow rate thereof is controlled over a wide range to obtain a mobile phase liquid. The mobile phase liquid thus obtained is introduced into the columns 1a and 1b so that the sample is separated in the columns and the biopolymer is collected in a fraction collector 6. The columns 1a and 1b are alternately regenerated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.