Tetrahydro-imidazolylmethylcarbazolones and analogs thereof for treating 5-HT function disturbances
US4859662A · kind A · utility
15Cited by
5References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 7, 1988 |
| Grant date | Aug 22, 1989 |
| Priority date | — |
| Expiry date | Dec 7, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to compounds of the general formula (I): ##STR1## wherein Im represents an imidazolyl group of the formula: ##STR2## and the various substituents are defined hereinbelow. The compounds are potent and selective antagonists of the effect of 5-HT at 5-HT.sub.3 receptors and are useful, for example, in the treatment of psychotic disorders, anxiety, and nausea and vomiting.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.