Quaternary derivatives of noroxymorphone which relieve nausea and emesis
US4861781A · kind A · utility
131Cited by
1References
10Claims
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Assignee
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Key dates
| Filing date | Sep 3, 1987 |
| Grant date | Aug 29, 1989 |
| Priority date | — |
| Expiry date | Sep 3, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/485
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Quaternary derivatives of noroxymorphone are used to prevent or relieve nausea and emesis associated with the use of narcotic analgesics without interfering with the analgesic activity of the drugs. A particularly preferred compound is methylnaltrexone. The compound is administered in a concentration between 0.05 mg/kg and 1.0 mg/kg prior to or concurrently with the administration of the narcotic analgesic.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.