Certain 2h-benzo[a]quinolizin-2-yl-aminoalkyl esters of 1,4-dihydro-3,5-pyridinedicarboxylates useful for treating circulation disorders

US4861782A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Eckhard Schwenner · Wuppertal, DE
• Hartmut Stegelmeier · Hilden, DE
• Stanislav Kazda · Wuppertal, DE
• Andreas Knorr · Erkrath, DE

Key dates

• Filing date: Feb 25, 1987
• Grant date: Aug 29, 1989
• Expiry date: Feb 25, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D455/06
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Circulation active compounds of the formula ##STR1## in which R.sup.1 is phenyl or heterocyclyl substituted by nitro, trifluoromethyl or other radicals, PA1 R.sup.2 is optionally substituted alkyl or other radical PA1 R.sup.3 and R.sup.5 are hydrogen, methyl or other radicals, PA1 R.sup.4 is hydrogen or optionally substituted alkyl, PA1 X is from 2 to 15, and PA1 R.sup.6 is ##STR2## and physiologically acceptable salts thereof.