Diabetic control by combined insulin forms
US4863896A · kind A · utility
40Cited by
2References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 13, 1988 |
| Grant date | Sep 5, 1989 |
| Priority date | — |
| Expiry date | Jan 13, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q11/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Peripherally administered insulin fails to provide liver hormone function. Hepatocyte directed vesicles with encapsulated insulin will restore liver function, but there is no non-targeted insulin to bypass the liver for peripheral use, as in natural, healthy body function. Whenever a prescribed dosage of insulin is divided between free and encapsulated hepatocyte targeted forms, a very small fraction of the dose in encapsulated form is sufficient to elicit full liver function, and non-targeted insulin supplies the needs of the body muscle and tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.