Methods of treating gout with chalcone derivatives
US4863968A · kind A · utility
7Cited by
9References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 14, 1988 |
| Grant date | Sep 5, 1989 |
| Priority date | — |
| Expiry date | Dec 14, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/165
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Certain chalcone derivatives are reported to inhibit the polymerization of tubulin to form microtubules and are therefore antimitotic agents which can be used as antigout agents. The chalcone derivatives are also reported to inhibit the destruction of the myelin sheath in the central nervous system of multiple sclerosis patients and are thus useful in controlling the progressive nature of the disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.