Preparation of 1-alkylimidazoles

US4864030A · kind A · utility

Assignee

• BASF SE

Inventors

• Hermann Koehler · Beindersheim, DE
• Toni Dockner
• Helmut Karn · Ludwigshafen, DE

Key dates

• Filing date: Aug 30, 1988
• Grant date: Sep 5, 1989
• Expiry date: Aug 30, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D233/90
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Process for the preparation of 1-alkylimidazoles of the general formula (I) ##STR1## where R.sup.1 is alkyl, R.sup.2 and R.sup.3 are hydrogen, alkyl, aryl, arylalkyl, or alkylaryl, R.sup.4 is carboxy, alkoxycarbonyl R.sup.5 OCC--, carbamoyl, or cyano, and R.sup.5 is an alkyl of from 1 to 8 carbon atoms--by the reaction of imidazoles of the general formula (II) ##STR2## with dialkyl sulfates of the general formula (III) EQU (R.sup.1 O).sub.2 SO.sub.2 (III) at elevated temperatures in the presence of a carboxylic acid or anhydride or of both acid and anhydride.