Treatment of allograft rejection with mycophenolic acid, its morpholinoethylester and derivatives thereof
US4868153A · kind A · utility
29Cited by
7References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 17, 1988 |
| Grant date | Sep 19, 1989 |
| Priority date | — |
| Expiry date | Aug 17, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The compounds and pharmaceutical compositions of Formula A, wherein Z is hydrogen or --C(O)R, Y is hydrogen or morpholinoethyl, and where R is lower alkyl or aryl, and the pharmaceutically acceptable salts thereof, are useful as immunosuppressive agents, particularly for treatment of allograft rejection, especially including cardiac allograft rejection, pancreatic allograft rejection and renal allograft rejection, and for treating autoimmune diabetes. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.