Pharmaceutical composition comprising an organic zinc complex and a process for preparing the active substance
US4868172A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1987 |
| Grant date | Sep 19, 1989 |
| Priority date | — |
| Expiry date | Apr 15, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention refers to a novel pharmaceutical composition having especially antimycotic activity and comprising the zinc complex of 5-chloro-7-iodo-8-hydroxyquinoline of formula (I) ##STR1## and one or more pharmaceutically acceptable carriers. The pharmaceutical composition of the invention can be used for the effective treatment of mycotic infections on the skin surface, mucous membranes or nails. The complex of formula (I) is prepared by reacting a solution of an alkali metal salt of 5-chloro-7-iodo-8-hydroxyquinoline with a solution containing an excess of an inorganic or organic zinc salt or a zinc complex having a lower stability constant than that of the complex of formula (I) and separating the product precipitated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.