Derivatives of 5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine

US4870079A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Susan F. Britcher · Norristown, US
• Wayne Thompson · Lansdale, US
• Terry A. Lyle · Lederach, US
• Sandor L. Varga · Harleysville, US

Key dates

• Filing date: Mar 30, 1988
• Grant date: Sep 26, 1989
• Expiry date: Mar 30, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Fluoro-and hydroxy-derivatives of 5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines wherein the substituents are on non-benzenoid carbons are active anticonvulsants and antagonists of N-methyl-D-aspartate.