Antihypercholesterolemic tetrazol-1-yl compounds
US4870187A · kind A · utility
6Cited by
3References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 23, 1988 |
| Grant date | Sep 26, 1989 |
| Priority date | — |
| Expiry date | Aug 23, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4 each are independently hydrogen, halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or trifluoromethyl; PA1 R is hydrogen, C.sub.1-4 alkyl or phenyl; PA1 A is ##STR2## R.sup.5 is hydrogen, a hydrolyzable ester group or a cation to form a non-toxic pharmaceutically acceptable salt, are novel antihypercholesterolemic agents which inhibit cholesterol biosynethesis. Intermediates and processes for their preparation are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.