Branched amides of L-aspartyl-D-amino acid dipeptides
US4870190A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 12, 1988 |
| Grant date | Sep 26, 1989 |
| Priority date | — |
| Expiry date | Oct 12, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06113
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Amides of L-aspartyl-D-amino acid dipeptides of the formula ##STR1## and physiologically acceptable cationic and acid addition salts thereof wherein R.sup.a is methyl, hydroxymethyl, ethyl, n-propyl or isopropyl; R is ##STR2## where at least one of R.sup.3, R.sup.4, R.sup.5, R.sup.6 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms, and the sum of the carbon atoms in R.sup.3, R.sup.4, R.sup.5 and R.sup.6 is not greater than six; and when both of R.sup.3 and R.sup.4 or R.sup.5 and R.sup.6 are alkyl, they are methyl or ethyl. Said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amine and amide intermediates useful in their production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.