Pharmaceutical compositions having antineoplastic activity
US4871528A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 7, 1987 |
| Grant date | Oct 3, 1989 |
| Priority date | — |
| Expiry date | Oct 7, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K33/243
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pharmaceutical compositions containing unit or separate dosages of 2.5 to 5 grams of reduced glutathione (GSH) and known anti-tumor agents, to be used simultaneously, separately or sequentially in anti-tumor therapy. Compounds of the invention, that can be used both in mono- or polychemotherapy, reach surprising results against tumors, thus avoiding the onset of dangerous side-effects, such as nephrotoxicity induced by cisplatinum, and increasing the long term survival rates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.