Patent · US Expired

Pharmaceutical compositions having antineoplastic activity

US4871528A · kind A · utility

18Cited by
0References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 7, 1987
Grant dateOct 3, 1989
Priority date
Expiry dateOct 7, 2007

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K33/243
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Pharmaceutical compositions containing unit or separate dosages of 2.5 to 5 grams of reduced glutathione (GSH) and known anti-tumor agents, to be used simultaneously, separately or sequentially in anti-tumor therapy. Compounds of the invention, that can be used both in mono- or polychemotherapy, reach surprising results against tumors, thus avoiding the onset of dangerous side-effects, such as nephrotoxicity induced by cisplatinum, and increasing the long term survival rates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.