Carboxy, carboalkoxy and carbamile substituted isonitrile radionuclide complexes
US4872561A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Dec 29, 1987 |
| Grant date | Oct 10, 1989 |
| Priority date | — |
| Expiry date | Dec 29, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A coordination complex comprising a radionuclide selected from the class consisting of radioactive isotopes of Tc, Ru, Co, Pt and Re and an isonitrile ligand of the formula: EQU (CNX)R, where X is a lower alkyl group having 1 to 4 carbon atoms, wherein R is selected from the group consisting of COOR.sup.1 and CONR.sup.2 R.sup.3 where R.sup.1 can be H, a pharmaceutically acceptable cation, or a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms. R.sup.2, and R.sup.3 can be H, or a substituted or unsubstituted alkyl group having 1 to 4 carbon atoms, and R.sup.2 and R.sup.3 can be the same of different is disclosed. Kits that can be used to form these complexes are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.