Hydrogels with increased organic solvent soluble active agent loading capacity, their preparation and the use thereof
US4873086A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 8, 1988 |
| Grant date | Oct 10, 1989 |
| Priority date | — |
| Expiry date | Aug 8, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S528/904
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An organic solvent soluble active agent containing water-insoluble hydrophilic hydrogel comprising a copolymer of (A) a water-soluble monoolefinic monomer or a mixture thereof optimally containing up to 50% thereof of one or more water-insoluble mono-olefinic monomers and (B) a terminally diolefinic hydrophobic macromer containing polypropylene oxide or polytetramethylene oxide units prepared in the presence of an effective macromer expanding amount of a macromer soluble compound of the formula EQU R'--R"--O.sub.n R"' where R', R", R"' and n are as defined in the claims, hydrogels useful in the loading of such active agents, their preparation, and use are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.