Process for preparing as partyl-phenylalanine dipeptides
US4873359A · kind A · utility
6Cited by
12References
4Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 1, 1987 |
| Grant date | Oct 10, 1989 |
| Priority date | — |
| Expiry date | Oct 1, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0613
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Synthesis of phenylserine ester (a) via benzaldehyde and glycine ester using serine hydroxymethyltransferase; and (b) via methyl benzoylacetate. Synthesis of hydroxy-aspartame or derivative by enzymatic coupling of phenylserine or derivative with aspartic acid or derivative. Hydrogenation of the coupled product to give as final product aspartame or analog with related processes and products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.