Patent · US Expired

Binder composition and analytical element having stabilized peroxidase in layer containing the composition

US4874692A · kind A · utility

8Cited by
12References
17Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJul 20, 1987
Grant dateOct 17, 1989
Priority date
Expiry dateJul 20, 2007

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/826
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An analytical element has a peroxidase-labeled ligand analog distributed within a layer comprising from 0.1 to 10.0 g/m.sup.2 of poly(vinyl-alcohol) and from 0.2 to 20.0 g/m.sup.2 of glycerol. The concentration of the glycerol must be greater than 1 times the concentration of poly(vinylalcohol) in the layer. As a result, the peroxidase retains more of its stability prior to use. Such elements can be used to determine a number of different immunologically reactive analytes, such as digoxin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.