Use of phosphoprotein patterns for diagnosis of neurological and psychiatric disorders
US4874694A · kind A · utility
21Cited by
3References
12Claims
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Key dates
| Filing date | Apr 7, 1987 |
| Grant date | Oct 17, 1989 |
| Priority date | — |
| Expiry date | Apr 7, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/25375
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A diagnostic method for neurological and psychiatric disorders utilizes the cerebrospinal fluid incubated in the presence of 32-P labelled ATP and an appropriate protein kinase. After termination of the reaction, a sample is applied to gels for electrophoresis. Subsequent autoradiography results in a disease-specific protein pattern that can be used for diagnosis of disorders such as Alzheimer disease, Huntington disease, Parkinson disease, dystonia ataxia, schizophrenia, epilepsy brain tumors, brain irradiation, head trauma, and acute and chronic encephalitic and vascular disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.