Polycyclic heterocyclic compounds, a process for their preparation and their use in human and veterinary medicine
US4874747A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 29, 1988 |
| Grant date | Oct 17, 1989 |
| Priority date | — |
| Expiry date | Apr 29, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q19/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A polycyclic heterocyclic compound has the formula ##STR1## wherein n is 1 or 2, PA0 R.sub.1 l represents (i) lower alkyl, (ii) --CH.sub.2 OH or (iii) ##STR2## R.sub.2 represents (a) hydrogen, (b) ##STR3## or (c)--OR.sub.3, R.sub.3 represents hydrogen, C.sub.1 -C.sub.20 alkyl mono or polyhydroxyalkyl, aryl or aralkyl optionally substituted, the residue of a sugar or ##STR4## wherein p is 1, 2, or 3, and r' and r" represent hydrogen, lower alkyl, mono or polyhydroxyalkyl, aryl optionally substituted, amino acid residue, aminated sugar residue, or together form a heterocycle, PA0 X represents oxygen, sulfur, SO, SO.sub.2 or --NR.sub.4, PA0 Y represents CR.sub.4 or a nitrogen atom and PA0 R.sub.4 represents hydrogen or lower alkyl. This polycyclic heterocyclic compound can be used in human and veterinary medicine and especially in the topical or systemic treatment of determatologic diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.