Chromatographic purification process
US4874843A · kind A · utility
22Cited by
5References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 3, 1987 |
| Grant date | Oct 17, 1989 |
| Priority date | — |
| Expiry date | Dec 3, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K7/08
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to a new chromatographic process for purifying fermentation products, particularly the antibiotic LY146032, from fermentation broths by use of a reverse phase non-functional resin. In the process of this invention the resin is loaded with the compound in the aqueous phase, the water then is removed from the resin and the resin converted to the organic phase for the resolution step. This process is applicable to purifying compounds which are adsorbed on reverse phase non-functional resins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.