Patent · US Expired

Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences

US4876187A · kind A · utility

229Cited by
5References
53Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 5, 1985
Grant dateOct 24, 1989
Priority date
Expiry dateDec 5, 2005

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6876
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A synthetic, non-naturally occurring molecule having the structure: EQU [NA.sub.1 --S--NA.sub.2 ].sub.n PA0 wherein NA.sub.1 and NA.sub.2 are noncomplementary nucleic acid sequences; PA0 wherein --S-- is a scissile linkage; and PA0 wherein n is an integer from 1 to 4. Variations of this molecule and methods for using the molecules for detecting nucleic acid sequences are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.