Stabilization of biological and pharmaceutical products during thermal inactivation of viral and bacterial contaminants
US4876241A · kind A · utility
52Cited by
11References
32Claims
0Family size
Assignee
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Key dates
| Filing date | May 18, 1988 |
| Grant date | Oct 24, 1989 |
| Priority date | — |
| Expiry date | May 18, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2/0005
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of inactivating pathogens in proteinaceous biological and pharmaceutical products which comprises: mixing the product in an aqueous solution with one or more primary stabilizers selected from the group consisting of sugars and sugar alcohols and one or more secondary stabilizers selected from the group consisting of sodium acetate, potassium acetate, lithium acetate, magnesium acetate, ammonium acetate, barium acetate, sodium sulfate, ammonium sulfate, lithium sulfate, potassium sulfate and magnesium sulfate; and subjecting said aqueous solution to a pathogen inactivating process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.