Attenuated pseudorabies virus which has a deletion in at least a portion of a repeat sequence and vaccine containing same
US4877737A · kind A · utility
17Cited by
2References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 6, 1985 |
| Grant date | Oct 31, 1989 |
| Priority date | — |
| Expiry date | Sep 6, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/948
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Attenuated pseudorabies viruses are provided which comprise DNA including a sequence essential for replication of the attenuated virus, at least a portion of which is present in a sequence essential for replication of a naturally-occurring pseudorabies virus, from which at least a portion of a repeat sequence has been deleted. These viruses are useful as vaccines for immunizing animals against pseudorabies virus disease. The invention also provides methods of preparing attenuated pseudorabies viruses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.