Selected difluoro derivatives
US4880780A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 4, 1987 |
| Grant date | Nov 14, 1989 |
| Priority date | — |
| Expiry date | Jun 4, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention discloses a series of difluoroketone, mono- di- and tri-peptide derivatives of formula Ia, Ib and Ic: ______________________________________ (Formula set out on pages following Examples) Ia (Formula set out on pages following Examples) Ib (Formula set out on pages following Examples) Ic ______________________________________ and salts thereof where appropriate, and wherein the radicals are defined hereafter in the specification. The derivatives are useful in inhibiting the action of human leukocyte elastase. There are also disclosed methods and intermediates for the manufacture of, and pharmaceutical compositions comprising, the said derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.