Heterocyclic amino compounds
US4880801A · kind A · utility
4Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 26, 1988 |
| Grant date | Nov 14, 1989 |
| Priority date | — |
| Expiry date | May 26, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D319/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the general formula (I) ##STR1## (R is H, alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl or CHO, R.sup.1 and R.sup.2 are independently halogen, alkyl, alkoxy, hydroxyl, cyano, nitro or --NR.sup.3 R.sup.4 where R.sup.3 and R.sup.4 are independently H or alkyl and R.sup.2 may be H) and their salts have selective .alpha..sub.2 -adrenoreceptor antagonist action. The compounds may be prepared by amination of compounds of the general formula (II) ##STR2## (where R.sup.1 and R.sup.2 are as defined above and X is a leaving group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.