Patent · US Expired

Substituted basic 2-aminotetralin useful as cardiotonic agents

US4880802A · kind A · utility

31Cited by

1References

10Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Rudolf Schohe · Wuppertal, DE
Thomas Glaser · Overath, DE
Jorg Traber · Lohmar, DE
George S. Allen · Nashville, US

Key dates

Filing date	Dec 8, 1987
Grant date	Nov 14, 1989
Priority date	—
Expiry date	Dec 8, 2007

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2603/74
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

For treatment of disorders of the central nervous system, the cardiovascular system or the intestinal tract, the new substituted basic 2-aminotetralins of the formula ##STR1## in which R.sup.1 represents hydrogen or alkyl, PA1 R.sup.2 represents hydrogen, alkyl or acyl, and PA1 R.sup.3 represents quinuclidine or a group of the formula --(CH.sub.2).sub.a --R.sup.4, --CH.sub.2 --CH.dbd.CH--(CH.sub.2).sub.b --R.sup.4, --CH.sub.2 --C.tbd.(CH.sub.2).sub.b --R.sup.4, ##STR2## wherein a denotes a number from 1 to 10, PA2 b denotes a number 0, 1, 2, 3 or 4, PA2 d denotes a number 2 or 3, and PA2 X denotes oxygen, sulphur, or NR.sup.5, and their salts.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.