Patent · US Expired

Mitomycin derivatives

US4880825A · kind A · utility

6Cited by
1References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 25, 1988
Grant dateNov 14, 1989
Priority date
Expiry dateMar 25, 2008

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/22
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Mitomycin derivatives having potent anti-tumor activity having the formula: ##STR1## wherein one of R.sub.1 and R.sub.2 represents carbamoyloxymethyl and the other represents hydrogen or R.sub.1 and R.sub.2 are bonded together to form methylene; PA1 X is hydrogen or halogen; PA1 Y is hydrogen or methyl; PA1 Z is hydrogen, methyl or acyl; and PA1 n is an integer of 2 or 3.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.