Method of, and apparatus for, NMR spectroscopic metabolite imaging and quantification
US4881032A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 21, 1988 |
| Grant date | Nov 14, 1989 |
| Priority date | — |
| Expiry date | Oct 21, 2008 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/3628
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for NMR spectroscopy metabolite imaging utilizes the steps of: applying to a desired portion of a sample a pulsed phase-encoding linear magnetic gradient signal in at least one of the three orthogonal dimensions of a Cartesian coordinate set, prior to acquisition of free-induction-decay NMR response signals from the sample portion; substantially eliminating from at least the sample portion eddy current fields induced responsive to the phase-encoding gradient pulses; maximizing the signal-to-noise ratio of the NMR response signals; and displaying the data resulting from Fourier transformation of the received response data. A high-field NMR imaging system is provided with self-shielded gradient coils, to subsantially remove eddy-current effects, and at least one of maximized-SNR antenna, of quadrature-driven volume RF coil and/or surface RF coil types are utilized for both transmission of the excitation RF pulses and reception of the RF response signals. The acquired FID data is filtered and a Fourier transform reconstruction, of dimension d' equal to one greater than the numder d of spatial dimensions to be displayed, is performed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.