Tissue imaging utilizing labelled steroids
US4882141A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 6, 1987 |
| Grant date | Nov 21, 1989 |
| Priority date | — |
| Expiry date | Nov 6, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J31/006
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for detecting a presence of steroid receptors in tissue therapeutically and for treating certian tissue, especially tissue having estrogen receptors, includes the step of treating the tissue by injection, surface application or the like, with a labeled steroid. The labeled steroid may include a moiety which is readily imageable on a gamma radiation detector, on x-ray film, on a fluoroscope, through NMR devices or the like. An especially suitable labeled steroid has been found to be 16-.sup.123 I-17-beta-estradiol having a specific activity of greater than 2,000 curies per millimole and preferably at least 5,000 curies per millimole.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.