Uricase and a method for the preparation thereof
US4882280A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 22, 1986 |
| Grant date | Nov 21, 1989 |
| Priority date | — |
| Expiry date | May 22, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/832
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Different from conventional uricase products, the uricase of the present invention has outstandingly high thermal stability and is active in a wide range of pH from 5 to 10 for the oxidative decomposition of uric acid undertaken in clinical analysis. The uricase of the invention is produced microbiologically by a thermophilic microorganism belonging to the genus of Bacillus and especially named as Bacillus sp. TB-90 which is a novel species distinguishable from any of the microorganisms belonging to the genus of Bacillus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.