Non-invasive near infrared measurement of blood analyte concentrations
US4882492A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 19, 1988 |
| Grant date | Nov 21, 1989 |
| Priority date | — |
| Expiry date | Jan 19, 2008 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/48
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A non-invasive apparatus and related method for measuring the concentration of glucose or other blood analytes utilizes both diffuse reflected and transmissive infrared absorption measurements and may be applied to either in vitro or in vivo sampling. The apparatus and method utilize non-dispersive correlation spectrometry and apply it to liquid blood serum analysis. Spectrally-modified near infrared light from the sample containing the analyte is split into two beams, one of which is directed through a negative correlation filter which blocks light in the absorption bands for the analyte to be measured, and the other of which is directed through a neutral density filter capable of blocking light equally at all wavelengths in the range of interest. Differencing the light intensity between the two light paths provides a measure proportional to analyte concentration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.