Condensation products of cyclic diketones and ascorbic acid as immunomodulatory agents
US4883808A · kind A · utility
5Cited by
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28Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 20, 1988 |
| Grant date | Nov 28, 1989 |
| Priority date | — |
| Expiry date | Jul 20, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D493/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
It has now been discovered that the acid catalyzed Michael reaction products of ascorbic acid and certain selected ketones are useful for their therapeutic activity. More specifically the useful reaction products of the invention are those obtained by reactions of ascorbic acid with .alpha.,.beta. unsaturated alicyclic diketones containing from 5 to 7 carbon atoms. The preferred compounds of the invention may be represented by the formula: ##STR1## wherein n is 1, 2 or 3. The ability of the compounds of this invention to stimulate an immune response has been established by a number of art recognized tests.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.