Composition for targeting, storing and loading of liposomes
US4885172A · kind A · utility
57Cited by
7References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 15, 1986 |
| Grant date | Dec 5, 1989 |
| Priority date | — |
| Expiry date | Dec 15, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/6913
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes a composition consisting of liposomes covalently or non-covalently coupled to the glycoprotein streptavidin. The streptavidin may additionally be coupled to biotinated proteins such as Immunoglobulin G or monoclonal antibodies. The liposomes of the invention may have a transmembrane potential across their membranes, and may be dehydrated. In addition, the composition may contain ionizable bioactive agents such as antineoplastic agents, and may be used in diagnostic assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.