Qunolyloxazole-2-ones useful as proteinkinase C inhibitors
US4886811A · kind A · utility
4Cited by
10References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 24, 1988 |
| Grant date | Dec 12, 1989 |
| Priority date | — |
| Expiry date | Oct 24, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to novel quinolyloxazole-2-ones which are useful as protein kinase C inhibitors, effective in the treatment of hypertension and asthma. This invention also includes a novel procedure for producing an intermediate ketone compound involving the reaction of a bromo-quinoline compound with butyl lithium and further reacting the lithiated compound with N-methyl-N-methoxyalkanamide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.