Dihydropyridine derivatives and pharmaceutical composition thereof
US4886819A · kind A · utility
6Cited by
6References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 20, 1987 |
| Grant date | Dec 12, 1989 |
| Priority date | — |
| Expiry date | Aug 20, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/90
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Dihydropyridine derivatives of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, A, B are defined as in the specification and nontoxic acid-addition salts thereof, have an excellent calcium blocking action (Ca-antagonist), and antihypertensive action, a platelet aggregation-inhibiting action, a phosphodiesterase-inhibiting action and the like, and thus are useful as a medicine, such as a coronary vasocilator, a cerebral hyperkinemic, antihypertensive, thrombosis-preventing or -treating agents, phosphodiesterase-inhibitor or the like. Pharmaceutical compositions and methods of use are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.