Stereospecific synthesis of [E]-alkenes from enamines via hydroboration
US4886924A · kind A · utility
4Cited by
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11Claims
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Key dates
| Filing date | Oct 17, 1988 |
| Grant date | Dec 12, 1989 |
| Priority date | — |
| Expiry date | Oct 17, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the stereospecific synthesis of [E] alkenes from enamines comprising the steps of hydroborating the enamine; esterifying the organoborane so formed and oxidizing the boronic ester in the presence of hydrogen peroxide and in the absence of added base under conditions sufficient to form the [E] alkene in high yield.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.