Synthetic gene for acyl carrier protein

US4888282A · kind A · utility

Assignees

• The United States of America, as represented by the Secretary of Agriculture · US
• PURDUE UNIVERSITY · US

Inventors

• Phillips D. Beremand · Peoria, US
• John B. Ohlrogge · Okemos, US
• David Kuhn · Uhingen, DE

Key dates

• Filing date: Jun 4, 1987
• Grant date: Dec 19, 1989
• Expiry date: Jun 4, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/415
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A synthetic gene which encodes for acyl carrier protein (ACP) has been designed. Construction, cloning, and expression in E. coli of spinach ACP-I has been demonstrated. In vitro production of ACP by appropriate expression vectors carrying the synthetic gene will augment the meager supply of this protein. Analogous genes designed for expression of ACP in plants would be a useful tool for controlling fatty acid synthesis and metabolism.