Production of gene and protein analogs through synthetic gene design using double stranded synthetic oligonucleotides
US4888286A · kind A · utility
49Cited by
1References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 24, 1987 |
| Grant date | Dec 19, 1989 |
| Priority date | — |
| Expiry date | Mar 24, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/65
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for the production of gene mutations and protein analogs using synthetic gene design and double-stranded synthetic oligonucleotide cassettes. The disclosure provides synthetic structural genes, synthetic double-stranded oligonucleotide cassettes and methods for the creation of synthetic gene analogs and polypeptide analogs by shortening or altering the native amino acid sequence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.