17-Substituted estradienes and estratrienes

US4891365A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Rudolf Wiechert · Berlin, DE
• Sybille Beier · Berlin, DE
• Walter Elger · Berlin, DE
• Klaus Annen · Berlin, DE
• Klaus Nickisch · Berlin, DE
• Henry Laurent

Key dates

• Filing date: Jul 2, 1987
• Grant date: Jan 2, 1990
• Expiry date: Jul 2, 2007

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

17-Substituted estradienes and estratrienes of Formula I ##STR1## wherein ##STR2## R is alkyl, alkenyl or cycloalkyl of up to 5 carbon atoms if ##STR3## R is hydrogen, alkyl, alkenyl or cycloalkyl of up to 5 carbon atoms if ##STR4## is a CC-single or CC-double bond, exhibit, an aldosterone-antagonistic activity and a strong gestagen potency.