Aminopropanol derivatives of 1,4:3,6-dianhydrohexitol nitrates, processes for their preparation and their use as medicaments

US4891373A · kind A · utility

Assignee

• PFIZER INC. · US

Inventors

• Peter Stoss · Illertissen, DE
• Matyas Leitold · Biberach, DE
• Rodney Yeates · Ramstein-Miesenbach, DE

Key dates

• Filing date: Nov 23, 1988
• Grant date: Jan 2, 1990
• Expiry date: Nov 23, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D493/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel aminopropanol derivatives of 1,4:3,6-dianhydro-hexitol nitrates of the general formula I ##STR1## in which X has the meaning given in the specification, processes for their preparation and their use in preventing and treating angina pectoris, systemic hypertension and pulmonary hypertension in mammals.