N-glycosylamide derivatives, processes for their preparation and their use as medicaments

US4891425A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Oswald Lockhoff · Cologne, DE
• Yutaka Hayauchi · Leverkusen, DE
• Peter Stadler · Haan, DE
• Helmut Brunner · Wuppertal, DE

Key dates

• Filing date: Jan 28, 1987
• Grant date: Jan 2, 1990
• Expiry date: Jan 28, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H15/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A N-glycosylamide derivative of the formula (I) ##STR1## in which R.sup.1 denotes hydrogen or a saturated or mono- or polyunsaturated alkyl radical with one to 50 carbon atoms, PA0 R.sup.2 denotes hydrogen or a saturated or mono- or polyunsaturated alkyl radical with one to 50 carbon atoms, PA0 R.sup.3 denotes hydrogen or an acyl radical with up to 20 carbon atoms, PA0 R.sup.4 denotes hydrogen or an alkyl radical with up to 4 carbon atoms and PA0 R.sup.5 and R.sup.6 independently of one another denote hydrogen or an acyl radical with up to 10 carbon atoms or a saturated or an unsaturated alkyl radical or an aralkyl radical with up to 10 carbon atoms, or PA0 R.sup.5 l and R.sup.6 together denote a grouping ##STR2## wherein R.sup.7 and R.sup.8 independently of one another denote hydrogen or lower alkyl with up to 5 carbon atoms or an unsubstituted or substituted aryl radical with up to 10 C atoms in the aromatic part. The N-glycosylamide derivatives exhibiting a broad defense-increasing action in the body.