Aromatic naphthyl compounds, a process for their preparation and their use in human and veterinary medicine and in cosmetic compositions
US4892940A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 22, 1987 |
| Grant date | Jan 9, 1990 |
| Priority date | — |
| Expiry date | May 22, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C65/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An aromatic naphthyl compound of the formula ##STR1## wherein n is 0 or 1, PA1 R' is hydrogen, OH, acyloxy, alkoxy or NH.sub.2, PA1 R" is hydrogen or lower alkoxy, or R' and R" taken together form an oxo, methano or hydroxy-imino radical, PA1 R is --CH.sub.2 OH or --COR.sub.8, PA1 R.sub.8 is hydrogen, --OR.sub.9 or ##STR2## R.sub.9 is hydrogen, alkyl having 1-20 carbon atoms, mono or polyhydroxyalkyl, aryl, aralkyl, the residue of a sugar or ##STR3## is 1, 2 or 3, PA1 r' and r" each independently represent hydrogen, alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl, benzyl, the residue of amino acid or the residue of aminated sugar, or r' and r" together form a heterocycle, PA1 R.sub.1, R.sub.2, R.sub.3 and R.sub.4 represent hydrogen, lower alkyl, alkoxy having 1-4 carbon atoms, fluoroalkoxy, CF.sub.3, cycloalkyl, lower acyl, halogen, OH, amino, acylamino or alkoxy carbonyl, PA1 R.sub.5, R.sub.6 and R.sub.7 represent hydrogen or methyl or when n=1, R.sub.5 and R.sub.7 taken together can form with the benzene ring a naphthalene ring, and the salts of the compound of formula I or their geometric or optical isomers. These compounds are useful in human and veterinary medicine and in cosm…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.