Patent · US Expired

Immunodiagnostic test for syphilis and other treponemal infections

US4894328A · kind A · utility

10Cited by
15References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 4, 1987
Grant dateJan 16, 1990
Priority date
Expiry dateMay 4, 2007

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/825
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A component for the rapid detection of anti-Treponema pallidum antibodies adapted for use as a selective foundation material in standard immunoassays is provided. The component comprises a quantity of fibronectin insolubilized to a solid matrix. The fibronectin component provides a foundation material for the selective binding of antigenic outer membrane proteins extracted from Treponema pallidum. Incorporation of the insolubilized fibronectin component bound to the antigenic outer membrane proteins extracted from Treponema pallidum into a standard immunoassay test pack provides an immunological assay for the presence of respective complementary anti-Treponema pallidum antibody in a biological sample.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.