Method of improving the yield of heterologous protein produced by cultivating recombinant bacteria
US4894334A · kind A · utility
11Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 6, 1987 |
| Grant date | Jan 16, 1990 |
| Priority date | — |
| Expiry date | Apr 6, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for improving the yield of heterologous protein such as ricin A toxin, produced by recombinant bacteria by supplementing the nutrient medium in which the bacteria are grown with an ethanol and/or amino acid mixture during the terminal phase of the cultivation. Also disclosed is a method for improving the yield of heterologous proteins under the control of the PL promoter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.