Antihypertensive phosphate derivatives
US4894367A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 18, 1988 |
| Grant date | Jan 16, 1990 |
| Priority date | — |
| Expiry date | Jul 18, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Antihypertensive phosphate derivatives having the following formula: ##STR1## wherein X is selected from one or more of C.sub.1 -C.sub.24 alkyl; C.sub.1 -C.sub.24 alkoxy; n and m are integers from 0 to 25 and the sum of which are less than or equal to 25; phenyl or substituted phenyl alkoxy, halogen, trifluoromethyl, phenyl, and substituted phenyl, phenoxy; and substituted phenoxy, wherein the substituents are C.sub.1 -C.sub.20 branched or straight chain alkyl, halogen, trifluoromethyl, phenyl and substituted phenyl; Q is selected from ##STR2## and --OR.sub.3 R.sub.1 is selected form hydrogen, C.sub.1 -C.sub.4 alkoxy and C.sub.1 -C.sub.4 alklyamino and R.sub.3 is C.sub.1 -C.sub.4 alkyl, with the provision that when Q is ##STR3## R.sub.1 is C.sub.1 -C.sub.4 branched or straight chain alkyl; T is a bivalent radical selected from alkylene or arylalkylene substituted at any position with one or more C.sub.1 -C.sub.10 alkyl with oxygen atom attached directly to the aromatic ring; Z is ##STR4## R.sub.2 is hydrogen or C.sub.1 -C.sub.4 branched straight chain alkyl; Q is an integer from 4-7.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.