Patent · US Expired

Immunosupressive analogues and derivatives of succinylacetone

US4895872A · kind A · utility

4Cited by
4References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 15, 1989
Grant dateJan 23, 1990
Priority date
Expiry dateMar 15, 2009

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/23
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Succinylacetone derived or related medicaments and methods of synthesis of the same are shown wherein the medicaments consists of succinylacetonyl-proline-PEG, succinylacetonyl-NH-PEG, or compounds that have the formula: ##STR1## and that have immunosuppressive activity both in vivo and in vitro based on their activities in cellular immunologic assays and adjuvant induced arthritis in rats, respectively.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.